Nanoparticulate Drug Delivery: A Newer Drug Delivery Concept

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Published

2023-07-04

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Issue

Vol. 4 No. 01 (2016): UP JOURNAL OF OPHTHALMOLOGY

Section

NEW INNORATIONS

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Copyright (c) 2023 UP JOURNAL OF OPHTHALMOLOGY

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Authors

  • Shri Kant .
  • Narendra Kumar Regar ,
  • Anushri Agrawal .
  • Sanjay Singh .

Abstract

Aim: To compare change in intravitreal drug concentr.ation with tinle for pristjne (plain)
and nanoparticulatedrug.
Method: Pristine drug solution & liposome nano-particulate prepared. Pristine & Nano particulate administered by topical, subtenon and intravitreally. Vitreous sample were collected at different interval & drug concentration was measured by High Performance Liquid Chromatography (HPLC).

Results: The concentration of drug in vitreous was more in intravitreal group as compared to subtenon group at different time interval. Nano particulate drug was present for long duration in vitreous as compared to pristine. 

conclusion: Nano particulate drug prolong the drug action and can reduce number of intravitreal injections as compared to pristine. 

How to Cite

1.
Kant S, Regar NK, Agrawal A, Singh S. Nanoparticulate Drug Delivery: A Newer Drug Delivery Concept. UPJO [Internet]. 2023 Jul. 4 [cited 2024 Oct. 16];4(01):73-8. Available from: https://upjo.org/index.php/upjo/article/view/315

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