Analysis of Retinal Nerve Fibre Layer Thickness with HtrAlc andBlood sugar levels in Type 2 Diabetes Mellitus patients without clinical diabetic retinopathy

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2023-07-04

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Vol. 5 No. 01 (2017): UP JOURNAL OF OPHTHALMOLOGY

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Original Article

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Copyright (c) 2023 UP JOURNAL OF OPHTHALMOLOGY

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Authors

  • Dcepak Soni lunior Resident, Ophthalmology. lN{S BHU
  • Diksha Prakash aonslLllan! Chdndra llyc Care
  • On Prakash Singh Maurya Profcssor. Dept. of Ophfialmolog], IMS, BHII
  • SuryaKumar Singh Profcssor. Dcpt. of Endocrinologv. IMS. BHII

Abstract

Objectives: The purpose of this study is to determine the correlation of retinal nerve fibre layer (RNFL) thickness with glycosylated haemoglobin (HbA1c) and blood sugar levels among Type 2 diabetic patients without clinical diabetic retinopathy. 

Methodology: This is a cross-sectional study involving 40 patients- Type 2 Diabetic patients without any evidence of diabetic retinopathy. A total of 80 eyes were observed. Evaluation of thickness of retinal nerve fibre layer along a 3.4mm diameter circle centred on the optic nerve head using SD-OCT in diabetic patients without clinical retinopathy. Comparison of the RNFL between patients with HbA1c <6, 6-7, >7 & with fasting blood sugar & post prandial blood sugar levels & which quadrant is maximally affected.

Results: The decrease in the thickness in the average RNFL thickness is affected by raised HbA1c levels, raised, Fasting Blood Sugar (FBS) & Post Prandial Blood Sugar (PPBS) levels (poor glycemic control).

Conclusion: Non proliferative Diabetic Retinopathy in type 2 Diabetes mellitus patients appears to have thinner RNFL thickness and is significantly correlated with high level of fasting & post prandial blood sugar levels & glycosylated haemoglobin levels.

How to Cite

1.
Soni D, Prakash D, Maurya OPS, Singh S. Analysis of Retinal Nerve Fibre Layer Thickness with HtrAlc andBlood sugar levels in Type 2 Diabetes Mellitus patients without clinical diabetic retinopathy. UPJO [Internet]. 2023 Jul. 4 [cited 2025 Feb. 23];5(01):5-12. Available from: https://upjo.org/index.php/upjo/article/view/323

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