A Comparative Study of Ocular Blood Flow Parameters in POAG, PACG and Controls in a Tertiary Care Eye Centre

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Published

2017-08-21

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Issue

Vol. 5 No. 01 (2017): UP JOURNAL OF OPHTHALMOLOGY

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Original Article

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Authors

  • Mohan Shalini MS,DNB, DubcyNoopur, MBBS
  • Gupta Ramesh Chandra MS, Kushwaha RN, MS
  • Khan Perwez
  • Singh Parul

Abstract

AIM

To measure ocular blood flow (OBF) in glaucoma patients using Color Doppler Imaging (CDI) and to compare the OBF parameters with age-matched controls.

METHOD

17 patients (34 eyes) with Primary open angle glaucoma (POAG), 14 patients (20 eyes) with Primary angle closure glaucoma (PACG) and 17 (34 eyes) controls were recruited. Peak systolic velocities (PSVs), end diastolic velocities (EDVs) and resistive indices (RIS) for the ophthalmic artery (OA), the central retinal artery (CRA) and the short posterior ciliary arteries (SPCAs) were measured using CDI.

RESULT

Mean age, mean Intraocular pressure (IOP), mean systolic blood pressure (SBP) and mean diastolic blood pressure (DBP) were comparable among the groups (p<0.05). In OA, mean PSVS (in cm/s) were 22.81±6.89, 23.72±3.31, 25.83±2.59; mean EDVs (cm/s) were 6.03±2.72, 7.87±1.35, 10.90±1.88 and mean RIs were 0.73±0.07, 0.66±0.04, 0.58 ±0.06 in POAG, PACG and Controls respectively. The difference in mean PSVs, mean EDVs and mean RIs was statistically significant between POAG vs controls (p<0.05) and between PACG vs controls but insignificant between POAG vs PACG.

In CRA, mean PSVs (cm/s) were 11.12±3.10, 9.27±2.35, 12.87±2.52; Mean EDVS (cm/s) were 3.33±1.18, 2.993±0.95, 5.75±0.88 and Mean RIs were 0.69±0.08, 0.68±0.04, and 0.53±0.05 in POAG, PACG and controls, respectively. The difference in mean PSVs, mean EDVs and mean RIs was statistically significant between POAG vs controls and PACG vs controls. The difference was statistically insignificant when same parameters were compared between POAG vs PACG.

In SPCAs, mean PSVs (cm/s) were 9.85±2.73, 9.58±1.85, 11.61±2.76; mean EDVs were 3.05+1.26, 4.21±1.26, 6.59±1.93 and mean RIs were 0.70±0.07, 0.56±0.08, 0.41±0.14 in POAG, PACG and controls respectively. The difference in mean PSVs, mean EDVs and mean RIs was statistically significant between POAG vs controls and between PACG vs controls.

CONCLUSION

Both POAG and PACG were consistently associated with decreased blood flow velocities and increased RIs in retro bulbar vessels. This association is more prominently seen in POAG as compared to PACG.

How to Cite

1.
Mohan Shalini, Chandra GR, Khan Perwez, Singh Parul. A Comparative Study of Ocular Blood Flow Parameters in POAG, PACG and Controls in a Tertiary Care Eye Centre. UPJO [Internet]. 2017 Aug. 21 [cited 2024 Oct. 16];5(01):13-21. Available from: https://upjo.org/index.php/upjo/article/view/325

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