Ocular Manifestation in Psoriasis

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Published

2023-11-22

DOI:

https://doi.org/10.56692/upjo.2023110302

Keywords:

Psoriasis, Dry eye, Uveitis, Ocular manifestations, Severity.

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Issue

Vol. 11 No. 03 (2023): UP JOURNAL OF OPHTHALMOLOGY

Section

Research Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

© UPJO, 2023 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.

Authors

  • Ajay K. Murthy Department of Orbit and Oculoplasty, Narayana Nethralaya, Bommasandra, Bangalore, Karnataka, India.
  • Subashini Kaliaperumal Jawaharlal Institute of Post Graduate Medical Education and Research, An Institution of National Importance, Government of India, Puducherry, India
  • Sandip Sarkar Jawaharlal Institute of Post Graduate Medical Education and Research, An Institution of National Importance, Government of India, Puducherry, India
  • Rashmi Kumari Jawaharlal Institute of Post Graduate Medical Education and Research, An Institution of National Importance, Government of India, Puducherry, India.

Abstract

Purpose: Psoriasis is a chronic autoimmune and systemic disease characterized by red and scaly plaques, affecting about 1% of the global population. Ocular involvement is becoming increasingly recognized as a complication of the disease. This study aims to evaluate ocular manifestations’ prevalence in psoriasis patients.
Methods: We conducted a prospective observational study of patients attending the outpatient department of dermatology in a multidisciplinary tertiary care hospital in South India. A total of 78 patients were enrolled in this study. Ocular symptoms, Schirmer’s test, tear breakup time, and intraocular pressure were assessed. The study used the psoriasis area and severity index (PASI) score to quantify the severity of lesions based on the area involved and the appearance of the plaque.
Results: The mean age of the patients was 48.5 ± 12.87 years. The mean duration of psoriasis was 4.8 ± 4.6 years. Ocular manifestations were more common in patients with PASI score >10 when compared to patients with PASI score ≤10. Among the patients with PASI score >10, 55 (70%) had ophthalmic manifestations such as cataracts, dryness, blepharitis, and tear breakup time. There was a statistically significant association between the PASI score and the prevalence of dry eye and blepharitis (p-value is 0.007 by Fischer exact test). There was no statistical significance in relation to the duration of disease and ophthalmic manifestations in our study population.
Conclusions: Symptoms of dry eye are a significant part of the clinical manifestations of the disease. Moreover, uveitis is a potentially serious complication in patients presenting with psoriatic arthritis.

How to Cite

1.
Murthy AK, Kaliaperumal S, Sarkar S, Kumari R. Ocular Manifestation in Psoriasis. UPJO [Internet]. 2023 Nov. 22 [cited 2024 Sep. 8];11(03):69-73. Available from: https://upjo.org/index.php/upjo/article/view/519

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