Superinfection of Mucormycosis in Post-COVID-19 Patients with Diabetes at Tertiary Care Hospital in Eastern Uttar Pradesh
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https://doi.org/10.56692/upjo.2024120104Keywords:
Amphotericin B, COVID-19, Diabetes, Immunocompromised, Mucormycosis.Dimensions Badge
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Copyright (c) 2024 Reena Sachan, Abhishek Singh, Aditi Garg, Divya Singh
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
© UPJO, 2023 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.
Introduction and Objectives: To determine the prevalence of mucormycosis in post COVID-19 patients. To understand the risk factor mainly diabetes and its association with post COVID-19 mucormycosis.Abstract
Method and Material: This a retrospective observational study of post-COVID-19 patients associated with mucormycosis which were managed in a tertiary care centre of Eastern UP from March 2021 to February 2022. The tissue sample for study was taken from surgical and medicine wards of the centre and the study was conducted in Microbiology Department. The procedures followed to process the sample were: 10% KOH mount after teasing the tissue. Culture on Sabouraud dextrose agar (SDA) with chloremphenicol and the fungal growth was stained with lactose phenol cotton blue (LPCB) for microscopy
Conclusion: There has been a surge in cases of mucormycosis in COVID-19 era. Uncontrolled diabetes and other immunocompromised states predispose to its development mainly in adult patients where diabetes is the most important predisposing factor. Although, early presentation and intervention play a very important part. Tight glycemic control, Amphotericin B and surgical debridement can lead to favourable outcomes.
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