Superinfection of Mucormycosis in Post-COVID-19 Patients with Diabetes at Tertiary Care Hospital in Eastern Uttar Pradesh

Abstract

Introduction and Objectives: To determine the prevalence of mucormycosis in post COVID-19 patients. To understand the risk factor mainly diabetes and its association with post COVID-19 mucormycosis.
Method and Material: This a retrospective observational study of post-COVID-19 patients associated with mucormycosis which were managed in a tertiary care centre of Eastern UP from March 2021 to February 2022. The tissue sample for study was taken from surgical and medicine wards of the centre and the study was conducted in Microbiology Department. The procedures followed to process the sample were: 10% KOH mount after teasing the tissue. Culture on Sabouraud dextrose agar (SDA) with chloremphenicol and the fungal growth was stained with lactose phenol cotton blue (LPCB) for microscopy
Conclusion: There has been a surge in cases of mucormycosis in COVID-19 era. Uncontrolled diabetes and other immunocompromised states predispose to its development mainly in adult patients where diabetes is the most important predisposing factor. Although, early presentation and intervention play a very important part. Tight glycemic control, Amphotericin B and surgical debridement can lead to favourable outcomes.