Pathophysiological Changes of Retinal Inner Layers in Diabetic Macular Edema

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Published

2021-07-25

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Issue

Vol. 9 No. 01 (2021): UP JOURNAL OF OPHTHALMOLOGY

Section

Deeper Insight

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Copyright (c) 2023 UP JOURNAL OF OPHTHALMOLOGY

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Authors

  • Malvika Singh .
  • Akshay Mohan
  • Sandeep Saxena

Abstract

Diabetic macular edema (DME) remains the major cause of vision loss in the highly prevalent type 2 diabetes. Retinal inner layers comprise of 4 layers, namely; ganglion cell layer -inner plexiform layer complex, inner nuclear layer and outer plexiform layer. Spectral domain optical coherence tomography (SD-OCT) is a non-invasive imaging tool for in vivo cross-sectional retinal histology. SD-OCT is an important tool in diagnosing and managing a patient with DME. Disorganization of retinal inner layers (DRIL) is defined as the failure to ascertain any of the inner retinal layers' boundaries. DRIL has been found to be a predictor of visual acuity (VA) in DME. Serial OCT scans demonstrating changes in DRIL correlate with the severity of diabetic retinopathy (DR). Many artificial intelligence softwares can read SD-OCT and identify DRIL to screen patients of DR.

How to Cite

1.
Singh M, Mohan A, Saxena S. Pathophysiological Changes of Retinal Inner Layers in Diabetic Macular Edema. UPJO [Internet]. 2021 Jul. 25 [cited 2025 Feb. 23];9(01):20-2. Available from: https://upjo.org/index.php/upjo/article/view/380

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