Optic Nerve Sheath Diameter in Glaucoma Patients and its Correlation with Intraocular Pressure

Published

2022-12-14

DOI:

https://doi.org/10.56692/upjo.2022100102

Keywords:

Glaucoma, Normal tension glaucoma, Optic nerve sheath diameter.

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Authors

  • Shalini Mohan Department of Ophthalmology, GSVM Medical college, Kanpur, Uttar Pradesh, India
  • Jayati Pandey Department of , GSVM Medical college, Kanpur, Uttar Pradesh, India
  • Anchal Tripathi Assistant Professor, 166 Military Hospital, Jammu, J&K, India
  • Ashok K. Verma Department of Radiology, GSVM Medical College, Kanpur, Uttar Pradesh, India

Abstract

Aim: To compare optic nerve sheath diameter (ONSD) in primary open angle glaucoma (POAG), primary angle closure glaucoma (PACG) and normal tension glaucoma (NTG). Material and Methods: Patients with POAG (n=38), PACG (n=32), NTG (n=18) and con-trols (n=48) underwent B-scan ultrasound and computed tomography scan (CT scan) measurement of ONSD. Intraocular pressure (IOP) was measured in all groups and was correlated with ONSD. Results: ONSD was significantly (p=<0.001) increased in NTG patients (mean=5.0 mm ± 0.48 SD) compared with POAG (mean=4.20 mm ± 0.32), PACG (mean=4.33 mm ± 0.27) and control (mean=4.21 mm ± 0.31). ONSD showed correlation with IOP in PACG group (r=0.392, p=0.02) while it did not in other groups. Conclusion: ONSD in a group of NTG patients were significantly increased compared with POAG, PACG and controls indicating the role of translaminar cribriform pressure gradient in NTG patients. Indirect measurement of ICP by assessment of ONSD may provide further insight into retrolaminar pressure component and pathophysiology of glaucoma.

How to Cite

1.
Mohan S, Pandey J, Tripathi A, Verma AK. Optic Nerve Sheath Diameter in Glaucoma Patients and its Correlation with Intraocular Pressure. UPJO [Internet]. 2022 Dec. 14 [cited 2024 Mar. 3];10(01):7-13. Available from: https://upjo.org/index.php/upjo/article/view/182

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