Therapeutic Role of Curcumin, a Traditional Indian Remedy in Various Ocular Disorders

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Published

2022-12-14

DOI:

https://doi.org/10.56692/upjo.2022100106

Keywords:

Antiinflammatory, Antioxidant, Curcumin

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Issue

Vol. 10 No. 01 (2022): UP JOURNAL OF OPHTHALMOLOGY

Section

REVIEW ARTICLE

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Copyright (c) 2022 UP Journal of Ophthalmology

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

© UPJO, 2023 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.

Authors

  • Ditsha Datta Department of Ophthalmology, GSVM Medical College Kanpur, Uttar Pradesh, India
  • Shalini Mohan Department of Ophthalmology, GSVM Medical College Kanpur, Uttar Pradesh, India
  • Namrata Patel Department of Ophthalmology, GSVM Medical College Kanpur, Uttar Pradesh, India
  • Ruchika Agrawal Department of Ophthalmology, Rama Medical College, Kanpur, Uttar Pradesh, India

Abstract

Curcumin (diferuloylmethane) derived from the rhizome of Curcuma longa L. has been an active ingredient of traditional Chinese medicine and Ayurvedic medicine for thousands of years to treat liver diseases, rheumatoid diseases, diabetes, atherosclerosis, infectious diseases and cancer. Curcumin has multiple essential pharmacological properties namely, antioxidant, anti-inflammatory, antimutagenic, antimicrobial and anticancer activity. Curcumin inhibits oxidative stress, angiogenesis and inflammatory processes and restore body homeostasis. Its effectiveness was also proved for major eye diseases. In this article, the influence of curcumin on various eye diseases such as dry eye disease, conjunctivitis, pterygium, anterior uveitis, glaucoma, cataract, age-related macular degeneration, diabetic retinopathy, corneal neovascularization, corneal wound healing are reported. Data analysis from several clinical and preclinical investigations indicate that curcumin is highly effective as a therapeutic agent in the treatment of various eye disorders.

How to Cite

1.
Datta D, Mohan S, Patel N, Agrawal R. Therapeutic Role of Curcumin, a Traditional Indian Remedy in Various Ocular Disorders. UPJO [Internet]. 2022 Dec. 14 [cited 2024 Oct. 11];10(01):28-35. Available from: https://upjo.org/index.php/upjo/article/view/187

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